The article is devoted to the study of the practices of adaptation of Agile Agile methodologies in corporate structures of IT companies and the analysis of their impact on management effectiveness. The article examines the theoretical foundations of Agile, the key values and principles that determine the flexibility of project teams, as well as the application features of the most common methodologies, including Scrum, Kanban and SAFe. Particular attention is paid to the problems of Agile scaling in conditions of a complex hierarchy, regulated processes and stable cultural attitudes. The barriers of adaptation associated with resistance to change, transformation of roles, the need for staff training and restructuring communication models are analyzed. Examples of successful Agile implementation in international corporations are given, demonstrating the impact of agile approaches on development speed, team interaction, and customer satisfaction. Based on the generalization of cases, the key factors of successful integration are identified and practical recommendations are formulated. The conclusion is made about the high prospects of Agile for increasing the efficiency, innovation activity and competitiveness of IT companies.